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Bioinformatics Scientist (m/f/d)
wanted of the next possible date at the Neuropathology department at Uniklinikum Heidelberg.
Heidelberg University Hospital (UKHD) is one of the leading medical centers in Germany. The Neuropathology Department at UKHD is a global pioneer in molecular genetic diagnostics for brain tumors and is committed to developing cutting-edge methods and rapidly implementing them for patients (e.g., Patel et al., Nat Med 2025; Ritter et al., Nat Cancer 2025; Sturm et al., Nat Med 2023; Maas et al., JCO 2021).

We provide the full spectrum of neuropathological diagnostics for local and international partner institutions in neurosurgery, neurology, pediatrics, and other disciplines. A particular focus lies on developing and implementing innovative molecular diagnostic techniques and delivering cutting-edge neuropathological support for clinical trials evaluating new therapeutic approaches.

We are looking for a versatile, conscientious, and highly motivated bioinformatician at the interface of molecular genetic-based research and routine diagnostic who is driven to make a tangible impact. You will work with rich and diverse sequencing datasets and joining a growing team of bioinformaticians and data scientists with the molecular neuropathology group. This role requires a proactive, independent working style. Beyond executing and adapting bioinformatics analyses, you will actively identify gaps, improve existing workflows, and development new analysis pipelines for both research and clinical diagnostics. A strong sense of responsibility for analytical quality, reproducibility, and clinical relevance is essential.
• Job-ID:
V000015233
• Field of application: Neuropathologie
• Location: Heidelberg
• Start date: as of now
• Job Category: Science and teaching
• Working hours: full-time (100 %)
• Published: 27.01.2026
• Limitation:Temporary
(2 years, extension is sought)
• Contract:TV-L

Your tasks

• Develop, maintain and operate bioinformatics workflows for the analysis of sequencing data (NGS and Nanopore).
• Optimize and further develop the bioinformatics infrastructure supporting molecular genetic analyses.
• Proactively identify methodological, technical, and workflow-related shortcomings in bioinformatics analyses and data pipelines; independently propose and implement improvements to analysis strategies, tools, automation and reporting.
• Develop and implement new analysis applications to support  research projects and clinical diagnostics.
• Collaborate closely with other bioinformaticians, laboratory scientists, and clinicians to ensure seamless integration of new methods, assays and end-to-end workflows.

Your profile

• Strong bioinformatics expertise and solid Linux proficiency, demonstrated through hands-on work in NGS data analysis and pipeline development
• Excellent programming skills, with practical experience in Python and workflow management using Snakemake (required) and Nextflow (preferred)). Additional R skills are a plus.
• In-depth knowledge of variant calling methods and tools; a background in biostatistics is adventagous
• Proven ability to work independently and take ownership of complex bioinformatic analyses, with a strong interest in clinical relevance and impact.
• Strong analytical and critical-thinking skills, with the motivation to challenge assumptions ans rigorously assess results and workflows.
• High initiative and strong problem awareness, including the ability to identify and drive improvements without explicit instruction.

What we offer

• Goal-oriented, individual training and development opportunities
• Working with the latest techniques / technical equipment
• Flexible working hours within the framework of flexitime
• Possibility to publish scientifically is offered and supported
• Regular team meetings
• Interdisciplinary cooperation with DKFZ and other collaborating institutes
• Possibility to take over project responsibility for  the diagnostics workflows and custom requests
• (Partial) project management / project responsibility possible if suitable
• Collectively agreed remuneration (TV-L E13), attractive company pension scheme (VBL)
• 30 days vacation
• Sustainable travel: job ticket
• Family-friendly working environment: cooperative arrangements for childcare, subsidy for child vacation care, advice for employees with relatives in need of care
• Wide range of health, prevention and sports offers

Contact & Application

For further information please contact Dr. Daniel Haag via e-mail or phone.

Interested?

Applications will be accepted until 16.02.2026 direct online.

Neuropathologie
Dr. Daniel Haag
Im Neuenheimer Feld 224
69120 Heidelberg
Daniel.Haag@med.uni-heidelberg.de

Note: The UKHD is subject to the provisions of the Infektionsschutzgesetz. Therefore, a valid measles immunity certificate is required for all persons employed at the UKHD.

The UKHD embraces diversity and values diversity.

Regardless of age, gender, sexual identity, disability, origin or religion, we offer everyone the same opportunities. If one gender is underrepresented in a particular area, we place particular emphasis on counteracting this imbalance. If they have the same aptitude, qualifications and professional performance, we give priority to people with severe disabilities when considering them for vacancies.

Classification is based on qualifications and personal requirements. The salary (gross) is for a full-time position and does not include the annual bonus or other allowances.